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A web server for interactive and zoomable Chaos Game Representation images

Kazuharu Arakawa*, Kazuki Oshita and Masaru Tomita

Author Affiliations

Institute for Advanced Biosciences, Keio University, Fujisawa, 252-8520, Japan

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Source Code for Biology and Medicine 2009, 4:6 doi:10.1186/1751-0473-4-6

Published: 17 September 2009

Abstract

Chaos Game Representation (CGR) is a generalized scale-independent Markov transition table, which is useful for the visualization and comparative study of genomic signature, or for the study of characteristic sequence motifs. However, in order to fully utilize the scale-independent properties of CGR, it should be accessible through scale-independent user interface instead of static images. Here we describe a web server and Perl library for generating zoomable CGR images utilizing Google Maps API, which is also easily searchable for specific motifs. The web server is freely accessible at http://www.g-language.org/wiki/cgr/ webcite, and the Perl library as well as the source code is distributed with the G-language Genome Analysis Environment under GNU General Public License.