|
Comparison of the siRNA_profile program and five other siRNA design programs |
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| siRNA_profile |
Deqor |
Ambion |
siDesign |
EMBOSS |
SiDirect |
|
|
|
||||||
| Number of hits |
6 (4) |
4(1) |
3(0) |
2(2) |
6(4) |
9(7) |
| Average GE%* |
10.4 |
14.8 |
21.1 |
13.0 |
21.6 |
14.8 |
| Median%* |
10.2 |
13.1 |
26.9 |
13.0 |
16.1 |
14.9 |
| Minimum GE%* |
5.4 |
10.3 |
8.1 |
12.6 |
6.7 |
5.8 |
| Maximum GE%* |
15.1 |
22.8 |
28.3 |
13.3 |
54.1 |
32.2 |
|
197 nt human CyclophilinB sequence and data of known siRNA efficacies [8] were used for siRNA design program comparison. Number of hits that were not selected by any of five other programs is shown in brackets (). * Gene expression (GE) % of the baseline | ||||||
Muhonen et al. Source Code for Biology and Medicine 2008 3:8 doi:10.1186/1751-0473-3-8 |
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